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The WUSTL release additionally stories that as part of their examine of remedy targets for Wolfram syndrome, Dr. Urano and his research team have moreover studied Dantrolene's results of on stem cells taken from Wolfram syndrome sufferers and their close family, equivalent to parents or siblings. They be aware that in contrast to adult stem cells collected from twine blood or stem cells developed from embryos, the stem cells examined in these studies have been grown from donor skin cells, and handled with progress factors so they would differentiate into particular cell varieties, such as neurons and insulin-producing cells.